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研究者総覧 学部データベース J-GLOBAL ORCID research map

    2023

  1. 様々な分野に適用可能な皮膚感作性試験法の開発

    臼井健二*, 宮﨑 洋, 山下 邦彦, 栢森 史浩, 有海秀人

    アレルギーの臨床 2023年11月号

    2023/10/20

  2. Shape control of Au nanostructures using peptides for biotechnological applications

    Shuhei Yoshida, Kin-ya Tomizaki, Kenji Usui*

    Chemical Communications, 59, 13239-13244 ※裏表紙掲載

    2023/11/07

    [Journal page] [Pubmed] [Back cover]

  3. Effect of linearly polarized microwaves on nanomorphology of calcium carbonate mineralization using peptides

    Kenji Usui*, Makoto Ozaki, Kan Hirao, Tsubasa Kosaka, Natsumi Endo, Shuhei Yoshida, Shin-ichiro Yokota, Yonejiro Arimoto, Ryuji Osawa, Nobuhiro Nakanishi, Kin-ya Tomizaki, Tomohiro Umetani, Fumihiro Kayamori*

    Scientific Reports, 13, 12027

    2023/07/13

    [journal page] [Pubmed]

  4. タンパク質の構造や酵素反応へのマイクロ波の影響

    栢森史浩*, 平尾莞, 鶴岡孝章, 中西伸浩, 臼井健二*

    日本電磁波エネルギー応用学会論文誌, 7, 1-9

    2023/12

    [journal page]

    5. 先頭へ

    2022

  5. De Novo Design of a Nanopore for Single-Molecule Detection That Incorporates a Beta-Hairpin Peptide

    Keisuke Shimizu, Batsaikhan Mijiddorj, Masataka Usami, Ikuro Mizoguchi, Shuhei Yoshida, Shiori Akayama, Yoshio Hamada, Akifumi Ohyama, Kenji Usui*, Izuru Kawamura, Ryuji Kawano

    Nature Nanotechnology, 17, 67-75

    2022/01

    [journal page] [Pubmed]

    6. 先頭へ

    2021

  6. マイクロ波照射による細胞への影響とその応用

    平田桃、川内敬子、西方敬人、中西伸浩、臼井健二*

    日本電磁場エネルギー応用学会論文誌, 5, 38-48

    2021/12

    [Journal page]

  7. ウォッシャーディスインフェクターのすすぎ排水中に含まれる洗浄剤残留量の測定によるすすぎ性能評価

    三軒隼人、藤田敏、川田原瑠勇、武川公、臼井健二、原田陽滋

    医療機器学, 91, 315-332

    2021/08

    [Journal page]

  8. 総合研究所研究チーム研究
    「生体への影響解析のための電磁波照射装置の開発と開発研究におけるアウトリーチ活動」

    臼井健二*、梅谷智弘

    甲南大学総合研究所叢書, 142, ISSN 2433-5851

    2021/03

    [PDF]

  9. 適用範囲の広い皮膚感作性試験法の開発

    臼井健二*、宮﨑洋、山下邦彦

    Medical Science Digest（北隆館／ニュー・サイエンス社）, 47, 226-228

    2021/03

    [Journal page]

  10. Intracellular Mineralization of Gold Nanoparticles Using Gold Ion-Binding Peptides with Cell-Penetrating Ability

    Makoto Ozaki, Shuhei Yoshida, Takaaki Tsuruoka, Kenji Usui*

    Chemical Communications, 57, 725-728 ※裏表紙掲載

    2021/01

    DOI: 10.1039/D0CC06117D
    [Journal page] [Pubmed] [Back cover]

  11. Elemental Composition Control of Gold-Titania Nanocomposites by Site-Specific Mineralization Using Artificial Peptides and DNA

    Makoto Ozaki, Takahito Imai, Takaaki Tsuruoka, Shungo Sakashita, Kin-ya Tomizaki, Kenji Usui*

    Communications Chemistry, 4, 1

    2021/01

    DOI: 10.1038/s42004-020-00440-8
    [Journal page]

    12. 先頭へ

    2020

  12. Effect of Tryptophan Residues on Gold Mineralization by a Gold Reducing Peptide

    Makoto Ozaki, Shuhei Yoshida, Maho Oura, Takaaki Tsuruoka, Kenji Usui*

    RSC Advances, 10, 40461-40466

    2020/11

    DOI: 10.1039/D0RA07098J
    [Journal page] [Pubmed]

  13. Mass Spectrometry-Based Solid Phase Peptide Reaction Assay for Detecting Allergenicity Using an Immobilized Peptide-Conjugating Photo-Cleavable Linker

    Hiroshi Miyazaki,Yasutaka Samejima, Kazuya Iwata, Yuuki Minamino, Shinya Hikida, Hideto Ariumi, Hidefumi Ikeda, Yoshio Hamada, Kunihiko Yamashita, Kenji Usui*

    International Journal of Molecular Sciences, 21, 8332

    2020/11

    DOI: 10.3390/ijms21218332
    [Journal page]

  14. Synthesis of Peptide-Immobilized Magnetic Beads, and Peptide Reactivity Assay for Assessing Skin Sensitization Utilizing Chromophore

    Hiroshi Miyazaki, Hikaru Takaishi, Hidefumi Ikeda, Hideto Ariumi, Yoshio Hamada, Kunihiko Yamashita, Kenji Usui*

    Processes, 8, 1257

    2020/09

    DOI: 10.3390/pr8101257
    [Journal page]

  15. Novel Purification Process for Amyloid Beta Peptide(1-40)

    Kenji Usui*,Shin-ichiro Yokota, Kazuya Iwata, Yoshio Hamada

    Processes, 8, 464 ※表紙掲載

    2020/04

    DOI: 10.3390/pr8040464
    [Journal page] [Cover Story] [Cover]

  16. Development of a Chromophore-Solid Phase Peptide Reaction Assay (C-SPRA) for Assessing Skin Sensitization In Vitro

    Hiroshi Miyazaki, Yoshio Hamada, Hikaru Takaishi, Yuuki Minamino, Hidefumi Ikeda, Hideaki Mekata, Masayuki Takaishi, Kunihiko Yamashita, Kenji Usui*

    Analyst, 145, 3211-3216 ※中裏表紙掲載

    2020/03

    DOI: 10.1039/C9AN02514F
    [Journal page] [Pubmed] [PDF]

    17. 先頭へ

    2018

  17. 第６節　ペプチド固定化樹脂を用いた皮膚感作性試験法の開発

    臼井健二*、宮﨑洋、南野祐槻、濵田芳男、山下邦彦

    皮膚の安全性・有用性評価法, 88-95

    2018/05

    ISBN: 978-4-86104-712-1-3047
    [Journal page]

  18. Channel Current Analysis Estimates the Pore-formation and the Penetration of Transmembrane Peptides

    Yusuke Sekiya, Shungo Sakashita Keisuke Shimizu, Kenji Usui*, Ryuji Kawano

    Analyst, 143, 3540-3543

    2018/05

    DOI: 10.1039/C8AN00243F
    [Journal page] [Pubmed] [Inside cover]

  19. Applications of a Novel Biodetection System to Saliva Using Protein Fingerprints with Data Processing

    Yuki Tominaga, Kenji Usui, Akiyoshi Hirata, Hiro-O Ito, Kiyoshi Nokihara

    Bioorganic & Medicinal Chemistry, 26, 3210-3216

    2018/04

    DOI: 10.1016/j.bmc.2018.04.049
    [Journal page] [PubMed]

  20. Editorial: Organic-Inorganic Hybrid Materials and Their Applications

    Kin-ya Tomizaki, Yoshio Hamada, Kenji Usui*

    Protein & Peptide Letters, 25, 2-3

    2018/04

    DOI: 10.2174/092986652501180418150844
    [Journal Page] [Pubmed]

  21. Peptides for Silica Precipitation: Amino Acid Sequences for Directing Mineralization

    Makoto Ozaki, Shungo Sakashita, Yoshio Hamada, Kenji Usui*

    Protein & Peptide Letters, 25, 15-24

    2018/04

    DOI: 10.2174/0929866525666171214111007
    [Journal page] [Pubmed]

  22. Modification of the N-Terminus of a Calcium Carbonate Precipitating Peptide Affects Calcium Carbonate Mineralization

    Kenji Usui*, Shin-ichiro Yokota, Makoto Ozaki, Shungo Sakashita, Takahito Imai, Kin-ya Tomizaki

    Protein & Peptide Letters, 25, 42-47

    2018/04

    DOI: 10.2174/0929866525666171221114658
    [Journal page] [Pubmed]

  23. Design of Anti-Alzheimer's Disease Agents Focusing on a Specific Interaction with Target Biomolecules

    Yoshio Hamada*, Kenji Usui

    Neuromethods, 132, 207-228

    2018

    DOI: 10.1007/978-1-4939-7404-7
    [Journal page]

    24. 先頭へ

    2017

  24. 生体分子の挙動解析研究を目標としたマイクロ波照射システムの開発
    ～ペプチドのバイオミネラリゼーションにおけるマイクロ波影響解析をモデルとして～

    臼井健二*、富樫浩行、圓東那津実、尾崎誠、有本米次郎、裏鍛武史、 大沢隆二、皆木幸一、中西伸浩、梅谷智弘*

    日本電磁波エネルギー応用学会論文誌, 17-24

    2017/12

    [Journal page]

  25. DNA G-Wire Formation Using an Artificial Peptide is Controlled by Protease Activity

    Kenji Usui*, Arisa Okada, Shungo Sakashita, Masayuki Shimooka, Takaaki Tsuruoka, Shu-ichi Nakano, Daisuke Miyoshi, Tsukasa Mashima, Masato Katahira, Yoshio Hamada

    Molecules, 22, 1991

    2017/11

    DOI: 10.3390/molecules22111991
    [Journal page] [PubMed]

  26. Non-Covalent Loading of Anti-Cancer Doxorubicin by Modularizable Peptide Self-Assemblies for a Nanoscale Drug Carrier

    Kin-ya Tomizaki*, Kohei Kishioka, Shunsuke Kataoka, Makoto Miyatani, Takuya Ikeda, Mami Komada, Takahito Imai, Kenji Usui*

    Molecules, 22, 1916

    2017/11

    DOI: 10.3390/molecules22111916
    [Journal page] [PubMed]

  27. マイクロビーズ固定化ペプチドを用いたバイオ計測デバイスの開発

    臼井健二*、南野祐槻、宮﨑洋、横田晋一朗、山下邦彦、濵田芳男

    医療・診断をささえるペプチド科学, 298-305

    2017/10

    [Journal page]

  28. Fluorescent and Luminescent Fusion Proteins for Analyses of Amyloid Beta Peptide Aggregation.

    Kenji Usui*, Masayasu Mie, Takashi Andou, Hisakazu Mihara, Eiry Kobatake

    Journal of Peptide Science, 23, 659-665

    2017/07

    DOI: 10.1002/psc.3003
    [Journal page] [PubMed]

    29. 先頭へ

    2016

  29. 有機-無機ハイブリッド材料創製を指向した人工ペプチドを用いたミネラリゼーションの制御

    臼井健二*、富﨑欣也

    化学工業, 67, 721-728

    2016/10

    [Journal page]

  30. Site-Specific Control of Multiple Mineralizations Using a Designed Peptide and DNA

    Kenji Usui*, Makoto Ozaki, Aoi Yamada, Yoshio Hamada, Takaaki Tsuruoka, Takahito Imai, Kin-ya Tomizaki

    Nanoscale, 8, 17081-17084 ※中裏表紙掲載

    2016/08

    DOI: 10.1039/c6nr03468c
    [Journal page] [PubMed] [Inside back cover]

  31. Site-Specific Control of Silica Mineralization on DNA Using a Designed Peptide

    Makoto Ozaki, Kazuma Nagai, Hiroto Nishiyama, Takaaki Tsuruoka, Satoshi Fujii, Tamaki Endoh, Takahito Imai, Kin-ya Tomizaki, Kenji Usui*

    Chemical Communications, 52, 4010-4013 ※中裏表紙掲載

    2016/03

    DOI: 10.1039/c5cc07870a
    [Journal page] [PubMed] [Inside back cover]

  32. A Cell Microarray Format: A Peptide Release System Using a Photo-Cleavable Linker for Cell Toxicity and Cell Uptake Analysis

    Kenji Usui*, Kin-ya Tomizaki, Hisakazu Mihara

    Methods in molecular biology, 1352, 199-210

    DOI: 10.1007/978-1-4939-3037-1_15
    [Journal page] [PubMed]

    33. 先頭へ

    2015

  33. 生体分子解析・細a胞解析に向けた設計ペプチドチップ

    臼井健二*、堤浩、三原久和

    バイオチップの基礎と応用, 143-152

    [Journal page]

  34. Label and Label-Free Detection Techniques for Protein Microarrays

    Amir Syahir, Kenji Usui*, Kin-ya Tomizaki, Kotaro Kajikawa, Hisakazu Mihara

    Microarrays, 4, 228-244

    2015/04

    DOI: 10.3390/microarrays4020228 [Journal page] [PubMed]

  35. Control of Guanine-Rich DNA Secondary Structures Depending on the Protease Activity Using a Designed PNA Peptide

    Kenji Usui*, Arisa Okada, Keita Kobayashi, Naoki Sugimoto

    Organic and Biomolecular Chemistry, 13, 2022-2025

    2015/02

    DOI: 10.1039/c4ob02535k
    [Journal page] [PubMed]

  36. ATP-Binding Peptide-Hydrogel Composite Synthesized by Molecular Imprinting on Beads

    Ayana Takata, Kenji Usui, Jun Matsui

    Molecular Imprinting, 3, 65-70

    [Journal page]

    37. 先頭へ

    2014

  37. Cellular Differentiation Assessments by Measuring the Degree of Cellular Internalization and Membrane Adsorption Using Designed Peptides.

    Kenji Usui*, Takuya Kikuchi, Kunio Kikuchi, Masayasu Mie, Eiry Kobatake, Hisakazu Mihara

    Bioorganic & medicinal chemistry letters, 24, 4129-4131

    2014/09

    DOI: 10.1016/j.bmcl.2014.07.053
    [Journal page] [PubMed]

  38. Peptides Targeting G-Quadruplex Structures

    Arisa Okada, Kenji Usui*

    Chemical Biology of Nucleic Acids:Fundamentals and Clinical Applications, 459-475

    [Journal page]

    39. 先頭へ

    2013

  39. A Novel Array Format for Monitoring Cellular Uptake Using a Photo-Cleavable Linker for Peptide Release

    Kenji Usui*, Takuya. Kikuchi, Kin-ya Tomizaki, Takashi Kakiyama, Hisakazu Mihara

    Chemical Communications, 49, 6394-6396

    2013/07

    DOI: 10.1039/c3cc41632a
    [Journal page] [PubMed]

  40. Systematic Screening of the Cellular Uptake of Designed Alpha-Helix Peptides

    Kenji Usui*, Takuya. Kikuchi, Masayasu Mie, Eiry Kobatake, Hisakazu Mihara

    Bioorganic & medicinal chemistry letters, 21, 2560-2567

    2013/05

    DOI: 10.1016/j.bmc.2013.02.030
    [Journal page] [PubMed]

  41. A Peptide Release System Using a Photo-Cleavable Linker in a Cell Array Format for Cell-Toxicity Analysis

    Takashi Kakiyama, Kenji Usui*, Kin-ya Tomizaki, Masayasu Mie, Eiry Kobatake, Hisakazu Mihara

    Polymer Journal, 45, 535-539

    [Journal page] [Pubmed]

    42. 先頭へ

    2012

  42. “オミクス”研究に向けた設計ペプチドアレイの構築

    臼井健二*、富崎欣也、三原久和

    分析化学 , 61, 523-534

    [Journal page]

    43. 先頭へ

    2011

  43. Use of a Designed Peptide Library to Screen for Binders to a Particular DNA G-Quadruplex Sequence

    Keita Kobayashi, Noriko Matsui, Kenji Usui*

    Journal of Nucleic Acids, 2011:572873

    DOI: 10.4061/2011/572873
    [Journal page] [PubMed]

  44. Cell Fingerprint Patterns Using Designed α-Helical Peptides to Screen for Cell-Specific Toxicity

    Kenji Usui*, Takashi Kakiyama, Kin-ya Tomizaki, Masayasu Mie, Eiry Kobatake, Hisakazu Mihara

    Bioorganic & medicinal chemistry letters, 21, 6281-6284

    2011/11

    DOI: 10.1016/j.bmcl.2011.09.002
    [Journal page] [PubMed]

  45. Thermodynamic Stability of Hoogsteen and Watson-Crick Base Pairs in the Presence of Histone H3-Mimicking Peptide

    Smritimoy Pramanik, Kaori Nakamura, Kenji Usui, Shu-ichi Nakano, Sarika Saxena, Jun Matsui, Daisuke Miyoshi, Naoki Sugimoto

    Chemical Communications, 47, 3967-3971

    2011/03

    DOI: 10.1039/c0cc05776b
    [Journal page] [PubMed]

    46. 先頭へ

    2010

  46. Protein-protein Interactions and Selection: Array-Based Techniques for Screening Disease-Associated Biomarkers in Predictive/Early Diagnosis

    Kin-ya Tomizaki, Kenji Usui, Hisakazu Mihara

    FEBS Journal, 277, 1996-2005

    2010/05

    DOI: 10.1111/j.1742-4658.2010.07626.x.
    [Journal page] [PDF] [PubMed]

  47. 第１０章　デザインペプチドを用いたプロテインアレイと細胞アレイ

    臼井健二*、富崎欣也、三原久和

    化学フロンティア２２ 生命現象を理解する分子ツール、(化学同人)、79-87

    2010/09

    [HP]

    48. 先頭へ

    2009

  48. Site-Specific Modification of Alzheimer's Peptides by Cholesterol Oxidation Products Enhances Aggregation Energetics and Neurotoxicity

    Kenji Usui, John D. Hulleman, Johan F. Paulsson, Sarah J. Siegel, Evan T. Powers, Jeffery W. Kelly

    Proceedings of the National Academy of Sciences of the United States of America, 106, 18563-18568

    2009/11

    DOI: 10.1073/pnas.0804758106
    [Journal page] [PDF] [PubMed]

  49. A Designed Peptide Chip: Protein Fingerprinting Technology with a Dry Peptide Array and Statistical Data Mining

    Kenji Usui, Kin-ya Tomizaki, Hisakazu Mihara

    Methods in molecular biology, 570, 273-284

    DOI: 10.1007/978-1-60327-394-7_13
    [Journal page] [PubMed]

  50. Proteins: Array-Based Techniques

    Kin-ya Tomizaki, Kenji Usui, Hisakazu Mihara

    Wiley Encyclopedia of Chemical Biology, 4, 144-158

    DOI: 10.1002/9780470048672.wecb022
    [Journal page]

  51. プロテインチップデバイス

    臼井健二・富崎欣也・三原久和

    超分子サイエンス&テクノロジー、(エヌ・ティー・エス)、1067－1075

    2009/05

    [HP]

  52. タンパク質・細胞分析用デザインペプチドチップ

    臼井健二・菊池卓哉・三原久和

    シングルセル解析の最前線、(シーエムシー出版)、17-24

    [HP]

    53. 先頭へ

    2007

  53. Screening of Alpha-Helical Peptide Ligands Controlling a Calcineurin-Phosphatase Activity
    Kenji Usui, Kin-ya Tomizaki, Hisakazu Mihara
    Bioorganic & medicinal chemistry letters, 17, 167-171
    DOI: 10.1016/j.bmcl.2006.09.075
    2007/01
    [Journal page] [PubMed]
  54. Interactions between Peptides Containing Nucleobase Amino Acids and T7 Phages Displaying S. Cerevisiae Proteins
    Sinya Watanabe, Kin-ya Tomizaki, Tsuyoshi Takahashi, Kenji Usui, Kotaro Kajikawa, Hisakazu Mihara
    Biopolymers, 88, 131-140
    DOI: 10.1002/bip.20662
    [Journal page] [PubMed]
  55. ペプチドライブラリを用いるタンパク質相互作用検出チップ
    富崎欣也・臼井健二・三原久和
    Electrochemistry, 75, 981-985
    [Journal page] [CiNii]

    56. 先頭へ

    2006

  56. Protein-Fingerprint Data Mining of a Designed Alpha-Helical Peptide Array
    Kenji Usui, Kin-ya Tomizaki, Hisakazu Mihara
    Molecular BioSystems, 2, 417-420 ※表紙掲載
    2006/09
    [Journal page] [PubMed]
  57. A Novel Peptide Microarray for Protein Detection and Analysis Utilizing a Dry Peptide Array System
    Kenji Usui, Kin-ya Tomizaki, Takafumi Ohyama, Kiyoshi Nokihara, Hisakazu Mihara
    Molecular BioSystems, 2, 113-121
    DOI: 10.1039/b514263f
    2006/02
    [Journal page] [PubMed]
  58. A PNA-DNA Hybridization Chip Approach for the Detection of Beta-Secretase Activity
    Shusuke Sano, Kin-ya Tomizaki, Kenji Usui, Hisakazu Mihara
    Bioorganic & medicinal chemistry letters, 16, 503-506
    DOI: 10.1016/j.bmcl.2005.10.064
    2006/02
    [Journal page] [PubMed]

    59. 先頭へ

    2005

  59. A Designed Glycopeptide Array for Characterization of Sugar-Binding Proteins toward a Glycopeptide Chip Technology
    Kenji Usui, Tetsunori Ojima, Kin-ya Tomizaki, Hisakazu Mihara
    Nanobiotechnology, 1, 191-200
    [Journal page]
  60. IR Study on Stacking Manner of Peptide Nanorings in Peptide Nanotubes
    Yukiko Nagai, Tsutomu Nakanishi, Hajime Okamoto, Kyozaburo Takeda, Yukio Furukawa, Kenji Usui, Hisakazu Mihara
    Japanese Journal of Applied Physics, 44, 7654-7661
    [Journal page]
  61. Difference in Self-Assembling Morphology of Peptide Nanorings
    Hajime Okamoto, Tetsuo Yamada, Hiroshi Miyazaki, Tsutomu Nakanishi, Kyozaburo Takeda, Kenji Usui,Ikuo Obataya, Hisakazu Mihara, Hiroaki Azehara, Wataru Mizutani, Katsushi Hashimoto, Hiroshi Yamaguchi, Yoshiro Hirayama
    Japanese Journal of Applied Physics, 44, 8240-8248
    [Journal page]
  62. Anomalous Reflection of Gold Applicable for a Practical Protein-Detecting Chip Platform
    Sinya Watanabe, Kenji Usui, Kin-ya Tomizaki, Kotaro Kajikawa, Hisakazu Mihara
    Molecular BioSystems, 1, 363-365
    DOI: 10.1039/b513075c
    2005/12
    [Journal page] [PubMed]
  63. Protein-Detecting Microarrays: Current Accomplishments and Requirements
    Kin-ya Tomizaki, Kenji Usui, Hisakazu Mihara
    ChemBioChem, 6, 782-799 ※表紙掲載
    DOI: 10.1002/cbic.200400232
    2005/05
    [Journal page] [PubMed]

    64. 先頭へ

    2004

  64. Peptide Arrays with Designed Alpha-Helical Structures for Characterization of Proteins from FRET-Fingerprint Patterns
    Kenji Usui, Mizuki Takahashi, Kiyoshi Nokihara, Hisakazu Mihara
    Molecular Diversity, 8, 209-218
    [Journal page] [PubMed]
  65. Peptide Arrays with Designed Secondary Structures for Protein Characterization Using Fluorescent Fingerprint Patterns
    Kenji Usui, Tetsunori Ojima, Mizuki Takahashi, Kiyoshi Nokihara, Hisakazu Mihara
    Biopolymers, 76, 129-139
    DOI: 10.1002/bip.10568
    [Journal page] [PubMed]
  66. ペプチドアレイを用いたプロテインチップの実用化を目指した研究
    軒原清史・大山貴史・臼井健二・米村耕一・富崎欣也・三原久和
    高分子論文集、61、523-532
    [PDF] [CiNii]
  67. Development of Peptide-Chips Focusing on a High Throughput Protein-Detection System
    Kiyoshi Nokihara, Takafumi Ohyama, Kenji Usui, Koichi. Yoneyama, Mizuki Takahashi, Hisakazu Mihara
    Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries, 83-88

    68. 先頭へ

    2003

  68. プロテインチップ
    臼井健二・三原久和
    化学装置2003年4月号、36-38
    [Journal page]
  69. ペプチドマイクロアレイ ～ペプチドライブラリを用いた新規プロテインチップの創製～
    臼井健二・三原久和
    Bioベンチャー 2003年7・8月号、3, 99-102
    [Journal page]

    70. 先頭へ