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業績

原著論文・総説・著作


    2025

  1. Development of detection system for lead ions in mixture solutions using UV-Vis measurements with peptide immobilized microbeads

    Shuhei Yoshida, Koki Yoshida, Yoshio Hamada, Takaaki Tsuruoka, Kenji Usui*

    Scientific Reports, 15, 3249

    2025/01/25

    [journal page]

    2. 先頭へ


    2024

  2. ナノバイオ分野におけるマイクロ波の影響に関する研究

    栢森 史浩, 中西 伸浩, 臼井 健二*

    色材協会誌, 97(6), 156-159

    2024/06/20

    DOI: 10.4011/shikizai.97.156
    [journal page]

  3. Development of a CaCO3 Precipitation Method Using a Peptide and Microwaves Generated by a Magnetron

    Fumihiro Kayamori, Hiroyuki Togashi, Natsumi Endo, Makoto Ozaki, Kan Hirao, Yonejiro Arimoto, Ryuji Osawa, Takaaki Tsuruoka, Takahito Imai, Kin-ya Tomizaki, Tomohiro Umetani, Nobuhiro Nakanishi, Kenji Usui*

    Processes, 12, 1327

    2024

    DOI: 10.3390/pr12071327
    [journal page]


    4. 2023

  4. タンパク質の構造や酵素反応へのマイクロ波の影響

    栢森史浩*, 平尾莞, 鶴岡孝章, 中西伸浩, 臼井健二*

    日本電磁波エネルギー応用学会論文誌, 7, 1-9

    2023/12

    DOI: 10.32304/jemeajournal.7.0_1
    [Journal page]

  5. Shape control of Au nanostructures using peptides for biotechnological applications

    Shuhei Yoshida, Kin-ya Tomizaki, Kenji Usui*

    Chemical Communications, 59, 13239-13244 ※裏表紙掲載

    2023/11/07

    DOI: 10.1039/d3cc04331b
    [Journal page] [Pubmed] [Back cover]

  6. 様々な分野に適用可能な皮膚感作性試験法の開発

    臼井健二*, 宮﨑 洋, 山下 邦彦, 栢森 史浩, 有海秀人

    アレルギーの臨床 2023年11月号、75-79

    2023/10/20

    [Journal page]

  7. Effect of linearly polarized microwaves on nanomorphology of calcium carbonate mineralization using peptides

    Kenji Usui*, Makoto Ozaki, Kan Hirao, Tsubasa Kosaka, Natsumi Endo, Shuhei Yoshida, Shin-ichiro Yokota, Yonejiro Arimoto, Ryuji Osawa, Nobuhiro Nakanishi, Kin-ya Tomizaki, Tomohiro Umetani, Fumihiro Kayamori*

    Scientific Reports, 13, 12027

    2023/07/13

    DOI: 10.1038/s41598-023-37473-7
    [Journal page] [Pubmed]

    8. 先頭へ


    2022

  8. De Novo Design of a Nanopore for Single-Molecule Detection That Incorporates a Beta-Hairpin Peptide

    Keisuke Shimizu, Batsaikhan Mijiddorj, Masataka Usami, Ikuro Mizoguchi, Shuhei Yoshida, Shiori Akayama, Yoshio Hamada, Akifumi Ohyama, Kenji Usui, Izuru Kawamura, Ryuji Kawano

    Nature Nanotechnology, 17, 67-75

    2022/01

    DOI: 10.1038/s41565-021-01008-w
    [Journal page] [Pubmed]


    9. 2021

  9. マイクロ波照射による細胞への影響とその応用

    平田桃、川内敬子、西方敬人、中西伸浩、臼井健二*

    日本電磁場エネルギー応用学会論文誌, 5, 38-48

    2021/12

    [Journal page]

  10. ウォッシャーディスインフェクターのすすぎ排水中に含まれる洗浄剤残留量の測定によるすすぎ性能評価

    三軒隼人、藤田敏、川田原瑠勇、武川公、臼井健二、原田陽滋

    医療機器学, 91, 315-332

    2021/08

    [Journal page]

  11. 総合研究所研究チーム研究
    「生体への影響解析のための電磁波照射装置の開発と開発研究におけるアウトリーチ活動」

    臼井健二*、梅谷智弘

    甲南大学総合研究所叢書, 142, ISSN 2433-5851

    2021/03

    [PDF]

  12. 適用範囲の広い皮膚感作性試験法の開発

    臼井健二*、宮﨑洋、山下邦彦

    Medical Science Digest（北隆館／ニュー・サイエンス社）, 47, 226-228

    2021/03

    [Journal page]

  13. Intracellular Mineralization of Gold Nanoparticles Using Gold Ion-Binding Peptides with Cell-Penetrating Ability

    Makoto Ozaki, Shuhei Yoshida, Takaaki Tsuruoka, Kenji Usui*

    Chemical Communications, 57, 725-728 ※裏表紙掲載

    2021/01

    DOI: 10.1039/D0CC06117D
    [Journal page] [Pubmed] [Back cover]

  14. Elemental Composition Control of Gold-Titania Nanocomposites by Site-Specific Mineralization Using Artificial Peptides and DNA

    Makoto Ozaki, Takahito Imai, Takaaki Tsuruoka, Shungo Sakashita, Kin-ya Tomizaki, Kenji Usui*

    Communications Chemistry, 4, 1

    2021/01

    DOI: 10.1038/s42004-020-00440-8
    [Journal page]

    15. 先頭へ


    2020

  15. Effect of Tryptophan Residues on Gold Mineralization by a Gold Reducing Peptide

    Makoto Ozaki, Shuhei Yoshida, Maho Oura, Takaaki Tsuruoka, Kenji Usui*

    RSC Advances, 10, 40461-40466

    2020/11

    DOI: 10.1039/D0RA07098J
    [Journal page] [Pubmed]

  16. Mass Spectrometry-Based Solid Phase Peptide Reaction Assay for Detecting Allergenicity Using an Immobilized Peptide-Conjugating Photo-Cleavable Linker

    Hiroshi Miyazaki,Yasutaka Samejima, Kazuya Iwata, Yuuki Minamino, Shinya Hikida, Hideto Ariumi, Hidefumi Ikeda, Yoshio Hamada, Kunihiko Yamashita, Kenji Usui*

    International Journal of Molecular Sciences, 21, 8332

    2020/11

    DOI: 10.3390/ijms21218332
    [Journal page]

  17. Synthesis of Peptide-Immobilized Magnetic Beads, and Peptide Reactivity Assay for Assessing Skin Sensitization Utilizing Chromophore

    Hiroshi Miyazaki, Hikaru Takaishi, Hidefumi Ikeda, Hideto Ariumi, Yoshio Hamada, Kunihiko Yamashita, Kenji Usui*

    Processes, 8, 1257

    2020/09

    DOI: 10.3390/pr8101257
    [Journal page]

  18. Novel Purification Process for Amyloid Beta Peptide(1-40)

    Kenji Usui*,Shin-ichiro Yokota, Kazuya Iwata, Yoshio Hamada

    Processes, 8, 464 ※表紙掲載

    2020/04

    DOI: 10.3390/pr8040464
    [Journal page] [Cover Story] [Cover]

  19. Development of a Chromophore-Solid Phase Peptide Reaction Assay (C-SPRA) for Assessing Skin Sensitization In Vitro

    Hiroshi Miyazaki, Yoshio Hamada, Hikaru Takaishi, Yuuki Minamino, Hidefumi Ikeda, Hideaki Mekata, Masayuki Takaishi, Kunihiko Yamashita, Kenji Usui*

    Analyst, 145, 3211-3216 ※中裏表紙掲載

    2020/03

    DOI: 10.1039/C9AN02514F
    [Journal page] [Pubmed] [PDF]

    20. 先頭へ

    2018

  20. 第６節　ペプチド固定化樹脂を用いた皮膚感作性試験法の開発

    臼井健二*、宮﨑洋、南野祐槻、濵田芳男、山下邦彦

    皮膚の安全性・有用性評価法, 88-95

    2018/05

    ISBN: 978-4-86104-712-1-3047
    [Journal page]

  21. Channel Current Analysis Estimates the Pore-formation and the Penetration of Transmembrane Peptides

    Yusuke Sekiya, Shungo Sakashita Keisuke Shimizu, Kenji Usui*, Ryuji Kawano

    Analyst, 143, 3540-3543

    2018/05

    DOI: 10.1039/C8AN00243F
    [Journal page] [Pubmed] [Inside cover]

  22. Applications of a Novel Biodetection System to Saliva Using Protein Fingerprints with Data Processing

    Yuki Tominaga, Kenji Usui, Akiyoshi Hirata, Hiro-O Ito, Kiyoshi Nokihara

    Bioorganic & Medicinal Chemistry, 26, 3210-3216

    2018/04

    DOI: 10.1016/j.bmc.2018.04.049
    [Journal page] [PubMed]

  23. Editorial: Organic-Inorganic Hybrid Materials and Their Applications

    Kin-ya Tomizaki, Yoshio Hamada, Kenji Usui*

    Protein & Peptide Letters, 25, 2-3

    2018/04

    DOI: 10.2174/092986652501180418150844
    [Journal Page] [Pubmed]

  24. Peptides for Silica Precipitation: Amino Acid Sequences for Directing Mineralization

    Makoto Ozaki, Shungo Sakashita, Yoshio Hamada, Kenji Usui*

    Protein & Peptide Letters, 25, 15-24

    2018/04

    DOI: 10.2174/0929866525666171214111007
    [Journal page] [Pubmed]

  25. Modification of the N-Terminus of a Calcium Carbonate Precipitating Peptide Affects Calcium Carbonate Mineralization

    Kenji Usui*, Shin-ichiro Yokota, Makoto Ozaki, Shungo Sakashita, Takahito Imai, Kin-ya Tomizaki

    Protein & Peptide Letters, 25, 42-47

    2018/04

    DOI: 10.2174/0929866525666171221114658
    [Journal page] [Pubmed]

  26. Design of Anti-Alzheimer's Disease Agents Focusing on a Specific Interaction with Target Biomolecules

    Yoshio Hamada*, Kenji Usui

    Neuromethods, 132, 207-228

    2018

    DOI: 10.1007/978-1-4939-7404-7
    [Journal page]

    27. 先頭へ


    2017

  27. 生体分子の挙動解析研究を目標としたマイクロ波照射システムの開発
    ～ペプチドのバイオミネラリゼーションにおけるマイクロ波影響解析をモデルとして～

    臼井健二*、富樫浩行、圓東那津実、尾崎誠、有本米次郎、裏鍛武史、 大沢隆二、皆木幸一、中西伸浩、梅谷智弘*

    日本電磁波エネルギー応用学会論文誌, 17-24

    2017/12

    [Journal page]

  28. DNA G-Wire Formation Using an Artificial Peptide is Controlled by Protease Activity

    Kenji Usui*, Arisa Okada, Shungo Sakashita, Masayuki Shimooka, Takaaki Tsuruoka, Shu-ichi Nakano, Daisuke Miyoshi, Tsukasa Mashima, Masato Katahira, Yoshio Hamada

    Molecules, 22, 1991

    2017/11

    DOI: 10.3390/molecules22111991
    [Journal page] [PubMed]

  29. Non-Covalent Loading of Anti-Cancer Doxorubicin by Modularizable Peptide Self-Assemblies for a Nanoscale Drug Carrier

    Kin-ya Tomizaki*, Kohei Kishioka, Shunsuke Kataoka, Makoto Miyatani, Takuya Ikeda, Mami Komada, Takahito Imai, Kenji Usui*

    Molecules, 22, 1916

    2017/11

    DOI: 10.3390/molecules22111916
    [Journal page] [PubMed]

  30. マイクロビーズ固定化ペプチドを用いたバイオ計測デバイスの開発

    臼井健二*、南野祐槻、宮﨑洋、横田晋一朗、山下邦彦、濵田芳男

    医療・診断をささえるペプチド科学, 298-305

    2017/10

    [Journal page]

  31. Fluorescent and Luminescent Fusion Proteins for Analyses of Amyloid Beta Peptide Aggregation.

    Kenji Usui*, Masayasu Mie, Takashi Andou, Hisakazu Mihara, Eiry Kobatake

    Journal of Peptide Science, 23, 659-665

    2017/07

    DOI: 10.1002/psc.3003
    [Journal page] [PubMed]

    32. 先頭へ


    2016

  32. 有機-無機ハイブリッド材料創製を指向した人工ペプチドを用いたミネラリゼーションの制御

    臼井健二*、富﨑欣也

    化学工業, 67, 721-728

    2016/10

    [Journal page]

  33. Site-Specific Control of Multiple Mineralizations Using a Designed Peptide and DNA

    Kenji Usui*, Makoto Ozaki, Aoi Yamada, Yoshio Hamada, Takaaki Tsuruoka, Takahito Imai, Kin-ya Tomizaki

    Nanoscale, 8, 17081-17084 ※中裏表紙掲載

    2016/08

    DOI: 10.1039/c6nr03468c
    [Journal page] [PubMed] [Inside back cover]

  34. Site-Specific Control of Silica Mineralization on DNA Using a Designed Peptide

    Makoto Ozaki, Kazuma Nagai, Hiroto Nishiyama, Takaaki Tsuruoka, Satoshi Fujii, Tamaki Endoh, Takahito Imai, Kin-ya Tomizaki, Kenji Usui*

    Chemical Communications, 52, 4010-4013 ※中裏表紙掲載

    2016/03

    DOI: 10.1039/c5cc07870a
    [Journal page] [PubMed] [Inside back cover]

  35. A Cell Microarray Format: A Peptide Release System Using a Photo-Cleavable Linker for Cell Toxicity and Cell Uptake Analysis

    Kenji Usui*, Kin-ya Tomizaki, Hisakazu Mihara

    Methods in molecular biology, 1352, 199-210

    DOI: 10.1007/978-1-4939-3037-1_15
    [Journal page] [PubMed]

    36. 先頭へ


    2015

  36. 生体分子解析・細a胞解析に向けた設計ペプチドチップ

    臼井健二*、堤浩、三原久和

    バイオチップの基礎と応用, 143-152

    [Journal page]

  37. Label and Label-Free Detection Techniques for Protein Microarrays

    Amir Syahir, Kenji Usui*, Kin-ya Tomizaki, Kotaro Kajikawa, Hisakazu Mihara

    Microarrays, 4, 228-244

    2015/04

    DOI: 10.3390/microarrays4020228 [Journal page] [PubMed]

  38. Control of Guanine-Rich DNA Secondary Structures Depending on the Protease Activity Using a Designed PNA Peptide

    Kenji Usui*, Arisa Okada, Keita Kobayashi, Naoki Sugimoto

    Organic and Biomolecular Chemistry, 13, 2022-2025

    2015/02

    DOI: 10.1039/c4ob02535k
    [Journal page] [PubMed]

  39. ATP-Binding Peptide-Hydrogel Composite Synthesized by Molecular Imprinting on Beads

    Ayana Takata, Kenji Usui, Jun Matsui

    Molecular Imprinting, 3, 65-70

    [Journal page]

    40. 先頭へ